A 2017 update article pdf available in gastroenterologie clinique et biologique 426 april 2018 with 5,355 reads how we measure reads. Wilsons disease is a rare inherited disorder that causes copper to accumulate in your liver, brain and other vital organs. With proper therapy, disease progress can be halted and oftentimes symptoms can be improved. Patients may become progressively sicker from day to day, so immediate treatment can be critical. The wilson s disease association funds research and facilitates and promotes the identification, education, treatment, and support of patients and other individuals affected by wilsons disease. Liverrelated symptoms include vomiting, weakness, fluid build up in the abdomen, swelling of the legs, yellowish skin and itchiness. Natural cure for wilsons disease and alternative treatments.
Homozygous, or, more commonly, compound heterozygous mutations lead to defective incorporation of copper into apoceruloplasmin and the subsequent formation of holoceruloplasmin, hampering. Although copper accumulation begins at birth, symptoms of the disorder only appear later in life. Wilson s disease is a genetic disorder in which excess copper builds up in the body. Symptoms are typically related to the brain and liver. Wilsons disease diagnosis and treatment mayo clinic. If you take medications for wilsons disease, treatment is lifelong. For severe liver damage, a liver transplant might be necessary. Treatment then focuses on preventing copper from building up again.
Wd was uniformly fatal until treatments were developed a halfcentury ago. Treatment for wilson disease is a lifelong process. Initially described by kinnear wilson in 1912, wilsons disease wd, or wilson disease, is the clinical condition resulting from mutations in the chromosome q14 in the region coding for the protein product atp7b, and occurs in a sporadic fashion as well as inherited as an autosomal recessive disease. Treatment is aimed at removing excess accumulated copper and preventing its reaccumulation. Wilson disease wd is a rare inherited disorder of copper metabolism in which excessive amounts of copper accumulate in the body. Wilsons disease treatment treatment includes medication that tends to decrease the copper absorption or remove excess of copper in the body. The buildup of copper leads to damage in the liver, brain, and eyes. The wda board of directors is composed of volunteers who are committed to the mission and vision of the wda. Wilson disease information page national institute of.